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primary human foreskin fibroblasts  (ATCC)


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    ATCC primary human foreskin fibroblasts
    Primary Human Foreskin Fibroblasts, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 21581 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/primary+human+foreskin+fibroblasts/Dulbecco's+Modified+Eagle's+Medium/pm42149941-160-0-5
    Average 99 stars, based on 21581 article reviews
    primary human foreskin fibroblasts - by Bioz Stars, 2026-09
    99/100 stars

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    Related Articles

    Modification:

    Article Title: Nuclear transport of cytomegalovirus tegument protein pp65 through nucleoplasmic reticulum.
    Article Snippet: .. Primary human foreskin fibroblasts (HFFs; ATCC-SCR-1041) were maintained in Dulbecco’s Modified Eagle Medium (DMEM; ATCC 30–2002) supplemented with 10% fetal bovine serum and 100IU/ml of Penicillin and Streptomycin. ..

    Article Title: AP2A1 modulates cell states between senescence and rejuvenation.
    Article Snippet: .. Primary human foreskin fibroblasts (HFF-1, ATCC) were cultured as a monolayer in high-glucose Dulbecco’s Modified Eagle’s Medium (DMEM, Wako) supplemented with 15 % fetal bovine serum (SigmaAldrich) and 1 % penicillin-streptomycin solution (Wako). .. Human mammary epithelial cells derived from normal breast tissue (MCF-10 A, ATCC) were cultured in DMEM/Ham’s F12 medium (Wako) supplemented with 5 % horse serum (Gibco), 0.25 IU/ml of insulin (Wako), 0.5 mg/ml of hydrocortisone (Wako), 100 ng/ml of cholera toxin (Wako), 20 ng/ml of EGF (Wako), and 1 % of penicillin-streptomycin solution; cells were cultured starting from passage 2 and used for experiments at passage 4.

    Article Title: The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites
    Article Snippet: .. T. gondii tachyzoites were maintained and cultured at 37 °C in 5% CO 2 in a humidified incubator using primary human foreskin fibroblasts (HFF, ATCC) maintained in Dulbecco’s modified Eagle medium (DMEM) (GibcoTM, Waltham, MA, USA) supplemented with 3.7 g/L sodium bicarbonate and 2.38 g/L HEPES, 10% Cosmic Calf serum (HycloneTM, Logan, UT, USA) and 20 mg/L gentamicin [ , ]. .. Growth inhibition was monitored by luminescence [ ], where 100 μL of culture medium without or with inhibitors, followed by 100 μL of DMEM containing 5000 parasites, were added to confluent monolayers of HFF cells in 96-well culture dishes (Eppendorf, Hamburg, Germany).

    Article Title: The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites.
    Article Snippet: .. T. gondii tachyzoites were maintained and cultured at 37 ◦C in 5% CO2 in a humidified incubator using primary human foreskin fibroblasts (HFF, ATCC) maintained in Dulbecco’s modified Eagle medium (DMEM) (GibcoTM, Waltham, MA, USA) supplemented with 3.7 g/L sodium bicarbonate and 2.38 g/L HEPES, 10% Cosmic Calf serum (HycloneTM, Logan, UT, USA) and 20 mg/L gentamicin [46,47]. .. Growth inhibition was monitored by luminescence [16], where 100 μL of culture medium without or with inhibitors, followed by 100 μL of DMEM containing 5000 parasites, were added to confluent monolayers of HFF cells in 96-well culture dishes (Eppendorf, Hamburg, Germany).

    Article Title: Nuclear transport of human cytomegalovirus tegument protein pp65 through nucleoplasmic reticulum
    Article Snippet: .. Primary human foreskin fibroblasts (HFFs; ATCC-SCR-1041) were maintained in Dulbecco’s Modified Eagle Medium (DMEM; ATCC 30–2002) supplemented with 10% fetal bovine serum and 100IU/ml of Penicillin and Streptomycin. ..

    Cell Culture:

    Article Title: AP2A1 modulates cell states between senescence and rejuvenation.
    Article Snippet: .. Primary human foreskin fibroblasts (HFF-1, ATCC) were cultured as a monolayer in high-glucose Dulbecco’s Modified Eagle’s Medium (DMEM, Wako) supplemented with 15 % fetal bovine serum (SigmaAldrich) and 1 % penicillin-streptomycin solution (Wako). .. Human mammary epithelial cells derived from normal breast tissue (MCF-10 A, ATCC) were cultured in DMEM/Ham’s F12 medium (Wako) supplemented with 5 % horse serum (Gibco), 0.25 IU/ml of insulin (Wako), 0.5 mg/ml of hydrocortisone (Wako), 100 ng/ml of cholera toxin (Wako), 20 ng/ml of EGF (Wako), and 1 % of penicillin-streptomycin solution; cells were cultured starting from passage 2 and used for experiments at passage 4.

    Article Title: The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites
    Article Snippet: .. T. gondii tachyzoites were maintained and cultured at 37 °C in 5% CO 2 in a humidified incubator using primary human foreskin fibroblasts (HFF, ATCC) maintained in Dulbecco’s modified Eagle medium (DMEM) (GibcoTM, Waltham, MA, USA) supplemented with 3.7 g/L sodium bicarbonate and 2.38 g/L HEPES, 10% Cosmic Calf serum (HycloneTM, Logan, UT, USA) and 20 mg/L gentamicin [ , ]. .. Growth inhibition was monitored by luminescence [ ], where 100 μL of culture medium without or with inhibitors, followed by 100 μL of DMEM containing 5000 parasites, were added to confluent monolayers of HFF cells in 96-well culture dishes (Eppendorf, Hamburg, Germany).

    Article Title: The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites.
    Article Snippet: .. T. gondii tachyzoites were maintained and cultured at 37 ◦C in 5% CO2 in a humidified incubator using primary human foreskin fibroblasts (HFF, ATCC) maintained in Dulbecco’s modified Eagle medium (DMEM) (GibcoTM, Waltham, MA, USA) supplemented with 3.7 g/L sodium bicarbonate and 2.38 g/L HEPES, 10% Cosmic Calf serum (HycloneTM, Logan, UT, USA) and 20 mg/L gentamicin [46,47]. .. Growth inhibition was monitored by luminescence [16], where 100 μL of culture medium without or with inhibitors, followed by 100 μL of DMEM containing 5000 parasites, were added to confluent monolayers of HFF cells in 96-well culture dishes (Eppendorf, Hamburg, Germany).

    other:

    Article Title: Viral entry shapes HCMV latency establishment.
    Article Snippet: Where indicated, primary monocytes were differentiated immediately following isolation by culturing in RPMI with 20% heat-inactivated fetal bovine serum (FBS), 2 mM L-glutamine and 100 units ml−1 penicillin and streptomycin (Beit-Haemek) supplemented with 50 ng/ml PMA (Sigma) for 3 days.



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    Image Search Results


    Expression of early damage and stress-response genes ( a ) FDXR , ( b ) GADD45A , ( c ) SESN1 , and ( d ) GDF15 in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 by ordinary one-way ANOVA followed by Dunnett’s post hoc test, comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Journal: Biomedicines

    Article Title: Mesenchymal Stem Cell–Derived Exosomes Mitigate Cutaneous Radiation Injury Through Coordinated Modulation of DNA Repair, Stress, and Inflammatory Gene Programs

    doi: 10.3390/biomedicines14040811

    Figure Lengend Snippet: Expression of early damage and stress-response genes ( a ) FDXR , ( b ) GADD45A , ( c ) SESN1 , and ( d ) GDF15 in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 by ordinary one-way ANOVA followed by Dunnett’s post hoc test, comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Article Snippet: Primary human dermal fibroblasts (HDFs) were purchased from PromoCell GmbH (SKU: C-12302; Heidelberg, Germany).

    Techniques: Expressing, Irradiation, Derivative Assay, Gene Expression, Control

    Expression of DNA repair and antioxidant genes ( a ) DDB2 , ( b ) RNF8 , and ( c ) SOD1 in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, *** p < 0.001, by ordinary one-way ANOVA followed by Dunnett’s post hoc test comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Journal: Biomedicines

    Article Title: Mesenchymal Stem Cell–Derived Exosomes Mitigate Cutaneous Radiation Injury Through Coordinated Modulation of DNA Repair, Stress, and Inflammatory Gene Programs

    doi: 10.3390/biomedicines14040811

    Figure Lengend Snippet: Expression of DNA repair and antioxidant genes ( a ) DDB2 , ( b ) RNF8 , and ( c ) SOD1 in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, *** p < 0.001, by ordinary one-way ANOVA followed by Dunnett’s post hoc test comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Article Snippet: Primary human dermal fibroblasts (HDFs) were purchased from PromoCell GmbH (SKU: C-12302; Heidelberg, Germany).

    Techniques: Expressing, Irradiation, Derivative Assay, Gene Expression, Control

    Expression of cell-cycle regulation and proliferation genes ( a ) CDKN1A , ( b ) CDKN2A , ( c ) MKI67 , ( d ) H2AFX , and ( e ) VEGFA in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 by ordinary one-way ANOVA followed by Dunnett’s post hoc test, comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Journal: Biomedicines

    Article Title: Mesenchymal Stem Cell–Derived Exosomes Mitigate Cutaneous Radiation Injury Through Coordinated Modulation of DNA Repair, Stress, and Inflammatory Gene Programs

    doi: 10.3390/biomedicines14040811

    Figure Lengend Snippet: Expression of cell-cycle regulation and proliferation genes ( a ) CDKN1A , ( b ) CDKN2A , ( c ) MKI67 , ( d ) H2AFX , and ( e ) VEGFA in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 by ordinary one-way ANOVA followed by Dunnett’s post hoc test, comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Article Snippet: Primary human dermal fibroblasts (HDFs) were purchased from PromoCell GmbH (SKU: C-12302; Heidelberg, Germany).

    Techniques: Expressing, Irradiation, Derivative Assay, Gene Expression, Control

    Expression of inflammatory response genes ( a ) IL-6 and ( b ) TNFAIP3 in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, **** p < 0.0001 by ordinary one-way ANOVA followed by Dunnett’s post hoc test, comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Journal: Biomedicines

    Article Title: Mesenchymal Stem Cell–Derived Exosomes Mitigate Cutaneous Radiation Injury Through Coordinated Modulation of DNA Repair, Stress, and Inflammatory Gene Programs

    doi: 10.3390/biomedicines14040811

    Figure Lengend Snippet: Expression of inflammatory response genes ( a ) IL-6 and ( b ) TNFAIP3 in irradiated HDFs (10 Gy) treated with exosomes (1 × 10 9 particles/mL) derived from BM-MSCs (BM-IR) and UC-MSCs (UC-IR), measured by qPCR. Gene expression was normalized to GAPDH and expressed as fold change relative to the non-irradiated Vehicle control at each timepoint. Data are shown as mean ± SD of three technical replicates from a representative experiment performed using a single HDF donor. * p < 0.05, ** p < 0.01, **** p < 0.0001 by ordinary one-way ANOVA followed by Dunnett’s post hoc test, comparing each treatment group to the Vehicle-IR control at the corresponding timepoint.

    Article Snippet: Primary human dermal fibroblasts (HDFs) were purchased from PromoCell GmbH (SKU: C-12302; Heidelberg, Germany).

    Techniques: Expressing, Irradiation, Derivative Assay, Gene Expression, Control

    TGC and/or unloaded CD NPs ameliorated the S. Typhimurium infected group induced histopathological alterations in mice’s liver tissues. Representative photomicrographs of the H&E-stained hepatic tissue sections showing the control (A), S. Typhimurium infected group (C), TGC (E), unloaded CD NPs (G), CD-TGC groups (I) and their respective higher magnifications (B, D, F, H, and J). A, B: control group displaying normal central vein (CV), hepatic cords (HC) with hepatocytes of eosinophilic granular cytoplasm (EC), rounded central single (SN) or double vesicular nuclei (DN), and kupffer cells (KC). C, D: S. Typhimurium infected group demonstrating multiple areas of variable-sized necrotic areas (NA) of coagulative necrosis (CN), severely dilated and congested sinusoid (SDS) with Kupffer cell hyperplasia (KCH). E, F: TGC group displaying moderately sized necrotic areas (MNA), moderately dilated and congested sinusoids (MDS), moderately hyperplastic Kupffer’s cells (MKC), interstitial mononuclear cell infiltration (MI), fibroblast proliferation (FP), and regenerated hepatocytes of stippling basophilic cytoplasm (BC) and pale nuclei (PN). G, H: unloaded CD NPs group showing a few scattered minute necrotic areas (mNA), intense mononuclear cell infiltration (IMI) around the portal area, and apparently normal hepatocytes (NH). I, J: CD-TGC group showed normal hepatocytes (NH), few dilated blood vessels (DBV), and a few interstitial lymphocytic aggregates (FL). Scale bars = 100 μm in A, C, E, G, I; and = 20 μm in B, D, F, H, and J. K: Bar charts demonstrate the statistical analysis of the comparative quantification of the hepatic injury scores in all studied groups. Bars carrying different superscript letters (a, b, c, d, and e) are significantly different as analyzed by the one-way ANOVA test, followed by the multiple comparisons by Duncan’s Post-hoc test ( p < 0.05). Values are the mean of 6 mice per group ± S.E.M.

    Journal: Scientific Reports

    Article Title: Chitosan-dextran sulfate nanocapsules for enhanced tigecycline efficacy against non-typhoidal Salmonella enterica

    doi: 10.1038/s41598-026-35229-7

    Figure Lengend Snippet: TGC and/or unloaded CD NPs ameliorated the S. Typhimurium infected group induced histopathological alterations in mice’s liver tissues. Representative photomicrographs of the H&E-stained hepatic tissue sections showing the control (A), S. Typhimurium infected group (C), TGC (E), unloaded CD NPs (G), CD-TGC groups (I) and their respective higher magnifications (B, D, F, H, and J). A, B: control group displaying normal central vein (CV), hepatic cords (HC) with hepatocytes of eosinophilic granular cytoplasm (EC), rounded central single (SN) or double vesicular nuclei (DN), and kupffer cells (KC). C, D: S. Typhimurium infected group demonstrating multiple areas of variable-sized necrotic areas (NA) of coagulative necrosis (CN), severely dilated and congested sinusoid (SDS) with Kupffer cell hyperplasia (KCH). E, F: TGC group displaying moderately sized necrotic areas (MNA), moderately dilated and congested sinusoids (MDS), moderately hyperplastic Kupffer’s cells (MKC), interstitial mononuclear cell infiltration (MI), fibroblast proliferation (FP), and regenerated hepatocytes of stippling basophilic cytoplasm (BC) and pale nuclei (PN). G, H: unloaded CD NPs group showing a few scattered minute necrotic areas (mNA), intense mononuclear cell infiltration (IMI) around the portal area, and apparently normal hepatocytes (NH). I, J: CD-TGC group showed normal hepatocytes (NH), few dilated blood vessels (DBV), and a few interstitial lymphocytic aggregates (FL). Scale bars = 100 μm in A, C, E, G, I; and = 20 μm in B, D, F, H, and J. K: Bar charts demonstrate the statistical analysis of the comparative quantification of the hepatic injury scores in all studied groups. Bars carrying different superscript letters (a, b, c, d, and e) are significantly different as analyzed by the one-way ANOVA test, followed by the multiple comparisons by Duncan’s Post-hoc test ( p < 0.05). Values are the mean of 6 mice per group ± S.E.M.

    Article Snippet: BJ normal human foreskin primary fibroblast cell line (ATCC CRL-2522) was used for studying safety of CD-TGC nanocapsules.

    Techniques: Infection, Staining, Control